R4RIN – MCQs, Mock Tests | Pharmacist Qualifying Examination[PEBC-Canada] PHYSIOLOGY: BLOOD MCQS

Normal haemoglobin is made up of

1. 2 alpha globin chains, 2 beta globin chains & 2 heme moieties
2. 2 alpha globin chains, 2 beta globin chains & 4 heme moieties
3. 2 alpha globin chains, 1 beta globin chain & 3 heme moieties
4. 4 alpha globin chains & 4 heme moieties

✅ Correct Answer: 2

The oxygen affinity of the Fe++ site in heme is increased by

1. acidosis
2. alkalosis
3. decreased NADH-metHb reductase activity
4. increased 2,3 bisphosphoglycerate

✅ Correct Answer: 2

Haematopoietic stem cells give rise to all these excep

1. : dendritic cells
2. Kupffer cells
3. mast cells
4. fibroblasts

✅ Correct Answer: 4

Haemolytic disease of the newborn

1. develops signs and symptoms after delivery
2. is most common in Asia
3. occurs in Rh D + infants of Rh D – mothers
4. occurs in Rh D - infants of Rh D + mothers

✅ Correct Answer: 3

The normal liver does not synthesise this protein

1. alpha feto protein
2. fibrinogen
3. immunoglobulin
4. insulin-like growth factor

✅ Correct Answer: 3

The intrinsic system of clotting factor activation requires

1. factor VIIa
2. HMW kininogen
3. tissue thromboplastin
4. von Willebrand factor

✅ Correct Answer: 2

Plasmin

1. is inhibited by tissue factor pathway inhibitor
2. is not present in normal blood vessels
3. is secreted by activated plasma cells
4. lyses fibrin and fibrinogen

✅ Correct Answer: 4

Lymphatic fluid

1. absorbs water-insoluble dietary fat
2. contains anticoagulant substances
3. does not normally contain white blood cells
4. has a higher protein content than plasma

✅ Correct Answer: 1

Platelets have

1. a half life in the circulation of 4 days
2. an average size of 1/10th that of a RBC
3. blood group antigens on their cell membranes
4. small, dense nuclei

✅ Correct Answer: 1

A haemolytic transfusion reaction will occur when

1. A blood is transfused into an AB patient
2. AB blood is transfused into an O patient
3. O positive blood is transfused into an O negative patient
4. O negative blood is transfused into an AB positive patient

✅ Correct Answer: 2