R4RIN – MCQs, Mock Tests | Biochemistry Biochemistry MCQS PAPER SET 8

An example of a transamination process is

1. glutamate = hexanoic acid + NH3
2. aspartate + hexanoic acid = glutamate + oxaloacetate
3. aspartate + α ketoglutarate = glutamate + oxaloacetate
4. glutamate = α-ketoglutarate + NH3

✅ Correct Answer: 3

Transamination is the process where

1. carboxyl group is transferred from amino acid
2. α-amino group is removed from the amino acid
3. polymerisation of amino acid takes place
4. none of the above

✅ Correct Answer: 2

The most toxic compounds is

1. tyrosine
2. phenylpyruvate
3. lysine
4. phenylalanine

✅ Correct Answer: 2

A person with phenylketonuria is advised not to consume which of the following products?

1. Glycine containing foods
2. Fat containing food
3. Glucose
4. Aspartame

✅ Correct Answer: 4

Tyrosine is degraded to acetoacetyl CoA and fumarate and is described as a

1. glucogenic amino acid
2. ketogenic amino acid
3. ketogenic and glucogenic amino acid
4. keto-gluco amino acid

✅ Correct Answer: 3

Transaminase enzymes are present in

1. liver
2. pancreas
3. intestine
4. none of these

✅ Correct Answer: 1

A person with phenylketonuria will convert

1. phenylalanine to phenylpyruvate
2. phenylalanine to isoleucine
3. phenylpyruvate to phenylalanine
4. tyrosine to phenylalanine

✅ Correct Answer: 1

An example of the oxidative deamination is

1. glutamate = hexanoic acid + NH3
2. aspartate + α-ketoglutarate = glutamate + oxaloacetate
3. glutamate = α-ketoglutarate + NH3
4. aspartate + hexanoic acid = glutamate + Oxaloacetate

✅ Correct Answer: 3

In the normal breakdown of phenylalanine, it is initially degraded to

1. fumarate
2. tyrosine
3. lysine
4. phenylpuruvate

✅ Correct Answer: 2

Transamination is the transfer of an amino

1. acid to a carboxylic acid plus ammonia
2. group from an amino acid to a keto acid
3. acid to a keto acid plus ammonia
4. group from an amino acid to a carboxylic acid

✅ Correct Answer: 2

Lysine is degraded to acetoacetyl CoA and is described as a

1. ketogenic amino acid
2. glucogenic amino acid
3. keto-gluco amino acid
4. none of these

✅ Correct Answer: 1

A ketogenic amino acid is one which degrades to

1. keto-sugars
2. either acetyl CoA or acetoacetyl CoA
3. pyruvate or citric acid cycle intermediates
4. multiple intermediates including pyruvate or citric acid cycle intermediates and acetyl CoA or acetoacetyl CoA

✅ Correct Answer: 2

A best described ketogenic amino acid is

1. lysine
2. tryptophan
3. valine
4. none of these

✅ Correct Answer: 1

A person suffering from phenylketonuria on consumption food containing high phenylalanine may lead to the accumulation of

1. phenylalanine
2. phenylpyruvate
3. tyrosine
4. isoleucine

✅ Correct Answer: 2

Which of the following mineral is involved in protein metabolism and oxidation reactions?

1. Molybdenum
2. Manganese
3. Magnesium
4. calcium

✅ Correct Answer: 1

Which of the following is not a function of iron?

1. Oxygen transport
2. Immune function
3. Brain function
4. Gene regulation

✅ Correct Answer: 4

Consumption of which nutrient leads to the multiplication of oral bacteria?

1. Fat
2. Carbohydrate
3. Protein
4. Fluoride

✅ Correct Answer: 2

Examples of goitrogenic foods are __________ and __________ .

1. turnips and corn
2. rutabagas and okra
3. raw cabbage and turnips
4. cassava and lettuce

✅ Correct Answer: 3

Which of the following carbohydrate is effective in promoting the calcium absorption?

1. Lactose
2. Maltose
3. Sucrose
4. Xylose

✅ Correct Answer: 1

What condition is caused by iodine deficiency during pregnancy and is characterized by stunted growth, deafness, and mental retardation?

1. Cretinism
2. Keshan disease
3. Multiple sclerosis
4. Crohn's disease

✅ Correct Answer: 1

Iodine is a part of thyroid hormone and is essential for the prevention of

1. goiter
2. osteoporosis
3. muscle weakness
4. diarrhea

✅ Correct Answer: 1

What transports copper from the intestinal cells to the liver?

1. Ceruloplasmin
2. Secretin
3. Acrolein
4. Albumin

✅ Correct Answer: 1

Which group is most often affected with copper deficiency?

1. Elderly woman
2. Alcoholics
3. Active toddlers with limited
4. Preterm infants food variety

✅ Correct Answer: 1

What is the main source of natural fluoride?

1. Mushrooms
2. Potatoes
3. Meat
4. Water

✅ Correct Answer: 4

Which of the following mineral is involved in the enzyme -controlled energy yielding reactions of metabolism?

1. Calcium
2. Phosphorus
3. Iron
4. Copper

✅ Correct Answer: 2

The mineral which aids in the utilization of iron and in hemoglobin synthesis is

1. Calcium
2. Phosphorus
3. cobalt
4. Copper

✅ Correct Answer: 4

The mineral which is considered important in maintaining electrical potential in nerves and membranes is

1. magnesium
2. manganese
3. Calcium
4. Iron

✅ Correct Answer: 1

Wilson's disease is an example of __________ and Menkes' syndrome is an example of __________ .

1. zinc deficiency; zinc toxicity
2. zinc toxicity; zinc deficiency
3. copper deficiency; copper toxicity
4. copper toxicity; copper deficiency

✅ Correct Answer: 4

Which of the following is correct?

1. Cobalt is part of vitamin B12.
2. Cobalt will not replace the need for vitamin B12 in humans
3. Both (a) and (b)
4. Cobalt will replace the need for vitamin B12 in humans

✅ Correct Answer: 3

Which of the following is required as a component of blood hemoglobin?

1. Iron
2. Magnesium
3. Calcium
4. Copper

✅ Correct Answer: 1

Adding __________ to a breakfast of cereal will help your body absorb iron.

1. milk
2. orange juice
3. coffe
4. water

✅ Correct Answer: 2

Which of the following ion is required for the development of sound teeth with resistance to tooth decay?

1. Fluoride ion
2. Sodium ion
3. Chloride ion
4. Magnesium ion

✅ Correct Answer: 1

Which of the following two beverages contribute 20 to 30 percent of our daily manganese intake?

1. Milk or tea
2. Cola or coffee
3. Tea or orange juice
4. Milk or orange juice

✅ Correct Answer: 1

An endemic disease of cardiomyopathy in children is attributed to

1. low Se in the environment
2. low intake of iron
3. high Se in the environment
4. high intake of iron

✅ Correct Answer: 1

Which of the following statement is correct?

1. Sodium and chloride are the chief extracellular ions of the body
2. Sodium and chloride are primarily involved in maintaining osmotic equilibrium and body fluid volume.
3. Chloride ion is necessary for the production of hydrochloric acid of gastric juice.
4. All of these

✅ Correct Answer: 4

Which of the following is necessary for the clotting of blood, functions of certain enzymes and control of fluids through cell membranes?

1. Calcium
2. Magnesium
3. Copper
4. All of these

✅ Correct Answer: 1

Selenium deficiency leads to

1. liver necrosis
2. diarrhea
3. multiple sclerosis
4. Crohn's disease

✅ Correct Answer: 1

Manganese is a key component of all of the following enzymes except

1. arginase
2. pyruvate carboxylase
3. ceruloplasmin
4. Mn-superoxide dismutase

✅ Correct Answer: 3

Which of the following vitamin is essential for the absorption of calcium from the intestinal tract?

1. Vitamin D
2. Vitamin E
3. Vitamin B12
4. Vitamin B6

✅ Correct Answer: 1

Which trace mineral is a component of the enzyme that activates vitamin A in the eye?

1. Zinc
2. Iron
3. Iodine
4. Chromium

✅ Correct Answer: 1

Chronic consumption of excess selenium can lead to

1. brittle hair and nails.
2. muscle weakness,
3. TPN
4. diarrhea.

✅ Correct Answer: 2

Normal glucose metabolism requires

1. chromium
2. manganese
3. magnesium
4. calcium

✅ Correct Answer: 1

Manganese is needed for

1. normal bone structure
2. reproduction and functioning of central nervous system
3. both (a) and (b)
4. muscle strengthening

✅ Correct Answer: 3

What is shielding in NMR?

1. Using a curved piece of metal to block an opponents attack
2. Putting metal around an Rf source
3. When the magnetic moment of an atom blocks the full induced magnetic field from surrounding nuclei
4. Blocking parts of a molecule from Rf radiation

✅ Correct Answer: 3

What is used to cool the superconducting coil?

1. Hydrogen
2. Ice
3. Dry ice
4. Liquid helium

✅ Correct Answer: 4

Coupling causes the peaks in 1H NMR spectra to be split into

1. two peaks
2. multiple peaks equal to the number of hydrogens on surrounding atoms
3. multiple peaks equal to the number of surrounding carbon atoms
4. multiple peaks equal to the number of hydrogen on surrounding atoms, plus one

✅ Correct Answer: 4

When placed in a magnetic field, all the random spins of the nuclei

1. stop
2. reverse direction
3. align with the magnetic field
4. rotate to 90° away from the induced field

✅ Correct Answer: 3

Better understanding of the nuclei is possible,

1. with the help of wavelength spectrum
2. with the help of frequencies ranges
3. with the help of a mathematical translator called the fourier transfer algorithm
4. none of the above

✅ Correct Answer: 3

All hydrogen atoms

1. have the same resonance frequency
2. resonate at different frequencies depending on their environment.
3. are attached to carbon
4. . resonate at about the same frequency as carbon

✅ Correct Answer: 2

Why is it important to use a deuterated solvent?

1. NMR uses least of this solvent
2. So the spectrometer can lock onto the sample to prevent the spectrum from drifting during aquisition
3. Expensive solvents work best with NMR
4. They dissolve polymer the fastest

✅ Correct Answer: 2

Which of the following is the basis of first dimension of separation for two-dimensional electrophoresis?

1. Molecular mass
2. Solubility
3. Isoelectric point
4. Folding

✅ Correct Answer: 3

What is meant by rotating frame of reference?

1. That the sample is spun rapidly in the applied field
2. If the laboratory itself is imagined to be rotated at the Larmor frequency, viewing that individual magnetic moment vectors are fixed in space
3. That the detector rotates around the sample
4. None of the above

✅ Correct Answer: 2

The sequence of amino acids in proteins can be determined by means of

1. identification of the -NH2 terminal amino acids
2. identification of the -COOH terminal amino acids
3. partial cleavage of the original polypeptide into smaller polypeptides
4. all of the above

✅ Correct Answer: 4

Why is it advantageous to record many FID signals from the same sample and then add them together?

1. To ensure that all target nuclei in the sample have been excited
2. To remove inaccuracies caused by fluctuations in the applied magnetic field
3. To increase sensitivity
4. None of the above

✅ Correct Answer: 3

In FT-NMR, how are nuclei excited?

1. By radio-frequency radiation whose frequency is swept across a predetermined range
2. By an intense pulse of radiation which contains a wide range of frequencies
3. By an intense pressure
4. None of the above

✅ Correct Answer: 1

What is the name given to the relaxation process due to an interaction between an excited nucleus and the magnetic fields caused by nuclei in molecules moving around in the sample?

1. Spin - lattice relaxation
2. Spin - spin relaxation
3. Spin - spin - spin relaxation
4. None of these

✅ Correct Answer: 1

Cytochrome C has an isoelectric pH of

1. 8.5
2. 10.05
3. 7.5
4. 11.05

✅ Correct Answer: 2

What does the Michelson interferometer do?

1. Split a polychromatic beam of radiation into its component wavelengths
2. Selectively filter certain wavelengths from a beam of I.R. radiation
3. Modulate the I.R. signal at a lower frequency, so that it can be observed by a detector
4. none of the above

✅ Correct Answer: 3

In scanning electron microscopy

1. a specimen is fixed and then coated with thin layer of a heavy metal
2. a specimen is fixed and then coated with transition metal
3. a specimen is not fixed and then coated with thin layer of a heavy metal
4. none of the above

✅ Correct Answer: 1

The frequency of precession, the transition frequency and the Larmor frequency are

1. different terms for the same frequency
2. same terms for the same frequency
3. different terms for the different frequency
4. same terms for the different frequency

✅ Correct Answer: 1

How do you turn a signal recorded in the time domain into a frequency domain signal?

1. Fourier transformation
2. Measurement of peak areas
3. By use of a Michelson interferometer
4. None of the above

✅ Correct Answer: 1

How many possible orientations do spin 1/2 nuclei have when they are located in an applied magnetic field?

1. 2
2. 4
3. 3
4. 6

✅ Correct Answer: 1

In immunofluroscence microscopy, fluroscent compounds are attached to

1. an antibody specific for the subcellular structure
2. an antigen specific for the subcellular structure
3. bound antibody specific for the subcellular structure
4. none of these

✅ Correct Answer: 1

An FT-IR instrument record a signal in the

1. time domain
2. frequency domain
3. both (a) and (b)
4. none of these

✅ Correct Answer: 1

When radiation energy is absorbed by a spin 1/2 nucleus in a magnetic field, what happens?

1. The processional frequency of the nucleus increases
2. The nucleus spins faster
3. The angle of precession flips so that the magnetic moment of the nucleus opposes the applied field
4. none of the above

✅ Correct Answer: 3

Negative staining is a technique used in

1. electron microscopy
2. gel electrophoresis
3. immunocytochemistry
4. light microscopy

✅ Correct Answer: 1

Which of the following is not used for detection in GC?

1. Infrared spectroscopy
2. NMR
3. Flame ionisation
4. Electrical conductivity

✅ Correct Answer: 2

Which of these effects result from slow injection of a large sample volume?

1. Increased resolution
2. Decreased resolution
3. Non-linear detector response
4. Constant resolution

✅ Correct Answer: 2

The GC trace obtained after an experiment is called a

1. chromatograph
2. chromatogram
3. chromatophore
4. graph

✅ Correct Answer: 2

Which of the following detectors give concentration-dependent signals?

1. Electron-capture detector
2. Thermal conductivity
3. Infra-red detector
4. . All of these

✅ Correct Answer: 4

What useful information can be found from a Van Deemter plot?

1. The selectivity factor
2. Optimum mobile phase flow rate
3. Optimum column temperature
4. Optimum column length

✅ Correct Answer: 2